GPCRdb

eticlopride

Agent/drug
Bioactivity

eticlopride

SMILES	CCc1cc(Cl)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O
InChIKey	AADCDMQTJNYOSS-LBPRGKRZSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	340.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb
Structure pdb	3PBL
Ligand site mutations	D₁ D₂ D₃ D₄

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	9.20	9.20	9.20	Guide to Pharmacology
D₂	DRD2	Rat	Dopamine	A	pKi	9.00	9.67	10.05	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKd	9.77	9.77	9.77	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	9.59	9.86	10.07	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.80	8.80	8.80	Guide to Pharmacology
D₃	DRD3	Human	Dopamine	A	pKi	9.80	9.90	9.97	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.00	7.00	7.00	Guide to Pharmacology
D₄	DRD4	Human	Dopamine	A	pKi	7.15	7.15	7.15	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pIC50	9.04	9.04	9.04	ChEMBL

Showing 1 to 1 of 1 entry

eticlopride

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb
Structure pdb	3PBL
Ligand site mutations	D₁ D₂ D₃ D₄

Compound is not listed as a drug.