Chembl4109258

Chemical Properties

SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(C(=O)O)c5c4[C@@]3(CCN1C)[C@H]2O5
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 475.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey DRGUKZYCXDRQEJ-IPRXQQHWSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 4.87 4.87 4.87 ChEMBL
κ OPRK Human Opioid A pKi 8.26 8.26 8.26 ChEMBL
κ OPRK Human Opioid A pEC50 6.81 6.81 6.81 ChEMBL
μ OPRM Human Opioid A pKi 7.27 7.27 7.27 ChEMBL
μ OPRM Human Opioid A pEC50 6.2 6.2 6.2 ChEMBL