CHEMBL1223951


SMILES NC(=O)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3Cc2ccccc2)c1
InChIKey NBLFFMILGMAYPO-OPVJXMOQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 7.4 7.4 7.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 4.56 4.56 4.56 ChEMBL
κ OPRK Human Opioid A pIC50 5.01 5.78 6.54 ChEMBL
μ OPRM Human Opioid A pIC50 4.97 4.97 4.97 ChEMBL