Chembl4111231


SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1)[C@H]2O5
InChIKey ADMSKYBLTWMPPO-QGUHJXFESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 433.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.86 7.86 7.86 ChEMBL
δ OPRD Human Opioid A pEC50 7.76 7.76 7.76 ChEMBL
κ OPRK Human Opioid A pKi 10.1 10.1 10.1 ChEMBL
κ OPRK Human Opioid A pEC50 9.08 9.08 9.08 ChEMBL
μ OPRM Human Opioid A pKi 8.88 8.88 8.88 ChEMBL
μ OPRM Human Opioid A pEC50 8.04 8.04 8.04 ChEMBL