CHEMBL4103044


SMILES O=C(c1ccoc1)N1C[C@H]2CC34CCC1C2C31CCN(CC2CC2)C4Cc2ccc(O)cc21
InChIKey LVZCCIOSHNXKHJ-FHRHOYQYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 444.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.5 9.5 9.5 ChEMBL
κ OPRK Human Opioid A pKi 9.66 9.66 9.66 ChEMBL
μ OPRM Human Opioid A pKi 9.34 9.34 9.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.64 9.64 9.64 ChEMBL
κ OPRK Human Opioid A pEC50 8.85 8.85 8.85 ChEMBL
μ OPRM Human Opioid A pEC50 6.81 6.81 6.81 ChEMBL