Chembl4111936


SMILES CC(C)[C@H]1C[C@H]2[C@H]3Cc4ccc(O)cc4[C@@]2(CCN3CC2CC2)CC1=O
InChIKey JIYAXHKPIXIXDQ-ZVXPMLRVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 9.48 9.48 9.48 ChEMBL
κ OPRK Human Opioid A pEC50 8.45 8.65 8.85 ChEMBL
μ OPRM Human Opioid A pKi 8.13 8.13 8.13 ChEMBL
μ OPRM Human Opioid A pEC50 8.44 8.54 8.64 ChEMBL