CHEMBL3975743


SMILES C[C@@H](CCCc1ccccc1)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1
InChIKey UXQWNSWYEJSWBM-GJWBGHMGSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 491.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 9.55 9.55 9.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 6.83 6.83 6.83 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 9.13 9.13 9.13 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 8.5 9.75 11.0 ChEMBL