Chembl4114409

Chemical Properties

SMILES Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(C)c3)n3c2CCO[C@H](CF)C3)ccn1
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight 435.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey OTEXRUHLALHTBR-QGZVFWFLSA-N

Database Connections

External Links

Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 8.3 8.3 8.3 ChEMBL