Chembl4116785


SMILES Oc1cccc(CCN(CCc2cccc(O)c2F)CC2CCC2)c1
InChIKey QKYSREYQMCTXND-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 9.92 9.92 9.92 ChEMBL
κ OPRK Human Opioid A pEC50 8.83 8.83 8.83 ChEMBL
μ OPRM Human Opioid A pKi 6.25 6.25 6.25 ChEMBL