CHEMBL4125975


SMILES Nc1nc(NCc2cccs2)nc2sc(-c3ccccc3)nc12
InChIKey LSZKDONVLXWTJB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 339.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Human Adenosine A pKi 6.95 6.95 6.95 ChEMBL
A2A AA2AR Human Adenosine A pKi 7.55 7.55 7.55 ChEMBL
A1 AA1R Human Adenosine A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pIC50 7.14 7.14 7.14 ChEMBL
A2A AA2AR Human Adenosine A pIC50 7.37 7.41 7.44 ChEMBL
A1 AA1R Human Adenosine A pIC50 7.29 7.29 7.29 ChEMBL