Chembl414838

Chemical Properties

SMILES O=C(NC/C=C/CN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(-c2cccnc2)cc1
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight 480.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey PAPJLFSOPBIPIF-OWOJBTEDSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.05 9.05 9.05 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL