Chembl414838
Chemical Properties
| SMILES | O=C(NC/C=C/CN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(-c2cccnc2)cc1 |
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 7 |
| Molecular weight | 480.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | PAPJLFSOPBIPIF-OWOJBTEDSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| D4 | DRD4 | Human | Dopamine | A | pKi | 6.28 | 6.28 | 6.28 | ChEMBL |
| D3 | DRD3 | Human | Dopamine | A | pKi | 9.05 | 9.05 | 9.05 | ChEMBL |
| D2 | DRD2 | Human | Dopamine | A | pKi | 7.26 | 7.26 | 7.26 | ChEMBL |