CHEMBL3991357


SMILES O=C(CCCN1CCCc2ccccc2C1)c1ccc(Cl)cc1
InChIKey ZLTIKXYTELEOBL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 327.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.35 6.36 6.36 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
H1 HRH1 Human Histamine A pKi 5.49 5.5 5.5 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.45 5.45 5.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database