CHEMBL404199


SMILES COc1cccc(OC)c1C1(C(=O)NS(=O)(=O)Cc2ccc(N3Cc4c(c(OCC(F)(F)F)c5cccnc5c4OCC(F)(F)F)C3=O)c(C)c2)CC1
InChIKey FJMQKJOWJVMHPQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 767.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Human Prostanoid A pKi 6.47 6.47 6.47 ChEMBL
IP PI2R Human Prostanoid A pKi 5.7 5.7 5.7 ChEMBL
DP1 PD2R Human Prostanoid A pKi 7.28 7.28 7.28 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 6.52 6.52 6.52 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 5.57 5.57 5.57 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 8.8 8.95 9.1 ChEMBL
TP TA2R Human Prostanoid A pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database