CHEMBL404372


SMILES C[C@@H]1NC(N)=Nc2cccc(Cl)c21
InChIKey XFMPGBXLGWZMQP-YFKPBYRVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 195.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 8.89 8.89 8.89 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.26 7.26 7.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database