CHEMBL4168691


SMILES N#Cc1c(CN2CCN(CCc3ccccc3)CC2)cn2ccccc12
InChIKey MZCGNTZTYZJMJK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.23 7.23 7.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.74 5.74 5.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database