CHEMBL4208744


SMILES O=C(NCCN1CCN(c2ccc(Cl)c(Cl)c2)CC1)c1ccccn1
InChIKey WJTVOECAMUQNOG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 378.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.21 6.21 6.21 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.74 9.74 9.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database