DESMETHYLOLANZAPINE


SMILES Cc1cc2c(s1)Nc1ccccc1N=C2N1CCNCC1
InChIKey FHPIXVHJEIZKJW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 298.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 7.66 7.66 7.66 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.69 6.69 6.69 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.05 8.05 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database