CHEMBL42231


SMILES COc1cccc(OC)c1OCCNCC1Cc2ccccc2C(c2ccccc2)C1
InChIKey BJGAWQMDTQOSCU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 7.04 7.04 7.04 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 6.96 6.96 6.96 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.91 7.91 7.91 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 6.54 6.64 6.75 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.29 9.29 9.29 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.77 7.77 7.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database