CHEMBL423018


SMILES COc1cc2nc3c(c(N)c2cc1OC)CC(CNC(=O)c1ccco1)C3
InChIKey XFNOYNVDQOQPCY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 367.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.1 7.1 7.1 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.8 6.8 6.8 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database