CHEMBL423181


SMILES COc1ccc2c(c1)CC(CCN1CCN(c3ccccn3)CC1)CC2
InChIKey MQYILSGYILZXMS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 5.76 5.76 5.76 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.8 9.8 9.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.8 9.8 9.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.68 8.06 8.45 ChEMBL