Chembl424371

Chemical Properties

SMILES Cc1cc(C)c(OCc2ccsc2S(=O)(=O)Nc2onc(C)c2Br)c(C)c1
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 470.0

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey KJBYBLYMXDYVRK-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Human Endothelin A pIC50 5.37 5.37 5.37 ChEMBL
ETA EDNRA Human Endothelin A pIC50 7.27 7.27 7.27 ChEMBL