CHEMBL426523


SMILES C[C@H]1CN2C[C@H](c3ccccc3)CC[C@H]2C[C@@]1(C)c1cccc(O)c1
InChIKey RGXBTFPNFYCKOY-QYAKYFNYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 335.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.51 7.51 7.52 ChEMBL
κ OPRK Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
μ OPRM Human Opioid A pKi 9.21 9.22 9.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 7.29 7.54 7.8 ChEMBL
κ OPRK Human Opioid A pIC50 8.49 8.71 8.92 ChEMBL
μ OPRM Human Opioid A pIC50 9.27 9.27 9.28 ChEMBL