CHEMBL4440301


SMILES CCCCN1CCN(c2cc(CC)cc(Cl)c2OC)CC1
InChIKey FWIXCSGJXQPKPA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.65 5.65 5.65 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.65 7.65 7.65 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.53 7.53 7.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 6.03 6.03 6.03 ChEMBL