CHEMBL4174189


SMILES CCOC(=O)CCN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)C3)CC1
InChIKey VPVXEPWFTGBGGT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 5.96 5.96 5.96 ChEMBL
H1 HRH1 Human Histamine A pKi 5.97 5.97 5.97 ChEMBL
H3 HRH3 Human Histamine A pKi 6.45 6.45 6.45 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.61 5.61 5.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database