Chembl4452046


SMILES CCCN(CCCCCc1ccc(O)c(OC)c1)[C@H]1CCc2nc(N)sc2C1
InChIKey PXPHOMJZPNVWMG-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.8 8.8 8.8 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D3 DRD3 Human Dopamine A pEC50 9.11 9.11 9.11 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.68 8.68 8.68 ChEMBL