CHEMBL444589


SMILES NC(C(=O)O)c1ccc(C(=O)O)c(O)c1
InChIKey GXZSAQLJWLCLOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 211.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pKi 4.52 4.52 4.52 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 4.7 4.7 4.7 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu4 GRM4 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 4.4 4.4 4.4 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 4.32 4.32 4.32 ChEMBL