Chembl4460573

Chemical Properties

SMILES Cc1cccc(C(=O)N2CCC(=CC#Cc3cccc(C)n3)CC2)c1
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight 330.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey GNTARZNMPMOBPT-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.86 5.86 5.86 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 7.95 7.95 7.95 ChEMBL