CHEMBL4206126


SMILES FC(F)(F)CCc1ccnc2c1CC[C@@H]1CNCCN21
InChIKey ZLOMTQBPDHCEQU-LLVKDONJSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 285.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 5.89 5.89 5.9 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.88 8.89 8.9 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.0 6.0 6.01 ChEMBL