Chembl4465959

Chemical Properties

SMILES COc1ccc(/C=C2\NC(=O)N(CCCCN3CCN(c4ccccc4OC)CC3)C2=O)cc1OC1CCCC1
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight 548.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey XRNYMDLTXKVPLN-DAFNUICNSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.66 6.66 6.66 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 7.21 7.24 7.27 ChEMBL