CHEMBL4457109


SMILES O=C1c2ccccc2S(=O)(=O)N1CCCCCCN1CCN(c2ccccc2Cl)CC1
InChIKey NWVWDVQASIRPNE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 461.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.35 7.35 7.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database