CHEMBL4471882


SMILES CCC(=O)NCc1cc(C(=O)NCCN2CCC(N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CC2)cc(C(=O)NCCN2CCN(CCCCC3CCN(CC(=O)N4c5ccccc5NC(=O)c5ccccc54)CC3)CC2)c1
InChIKey QRUXDRCXIGZTGT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 5
Rotatable bonds 20
Molecular weight (Da) 1076.6

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.96 6.96 6.96 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.57 8.57 8.57 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.55 7.55 7.55 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.44 9.44 9.44 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.56 8.56 8.56 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 9.09 9.09 9.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database