CHEMBL4483392


SMILES Cn1c(=O)c2c(nc3n2CCN(Cc2csc(-c4cccc(Cl)c4)n2)C3)n(C)c1=O
InChIKey JFIAUWNUIUKPBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 442.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 6.8 6.8 6.8 ChEMBL
A1 AA1R Rat Adenosine A pKi 6.36 6.36 6.36 ChEMBL
A2A AA2AR Human Adenosine A pKi 6.44 6.44 6.44 ChEMBL
A1 AA1R Human Adenosine A pKi 7.14 7.14 7.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database