CHEMBL425064


SMILES Fc1ccc(N2CCN(Cc3cn4cccnc4n3)CC2)cc1
InChIKey RISVNNDOXVACCB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.33 4.33 4.33 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.22 4.22 4.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.26 4.29 4.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database