CHEMBL1257811


SMILES Cc1ccc(C)c(C(=O)CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c1
InChIKey DRDXZCGSMVSSLQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.42 5.42 5.42 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.37 7.6 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database