CHEMBL1257927


SMILES Cc1ccc(C)c(C(=O)CCCN2CCC(O)(c3cc(C)ccc3C)CC2)c1
InChIKey YHNXVNWEANWEHW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 379.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.52 7.52 7.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.55 6.55 6.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.26 7.3 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database