Chembl4567758
Chemical Properties
| SMILES | O=C(NCCCN1CCN(c2ncccn2)CC1)NN(Cc1ccc(F)cc1)c1ccccc1 |
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 9 |
| Molecular weight | 463.3 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | YFIRTELZAMWIHL-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| D4 | DRD4 | Human | Dopamine | A | pKi | 7.72 | 7.72 | 7.72 | ChEMBL |
| D3 | DRD3 | Human | Dopamine | A | pKi | 5.72 | 5.72 | 5.72 | ChEMBL |
| D2 | DRD2 | Human | Dopamine | A | pKi | 6.37 | 6.44 | 6.51 | ChEMBL |