CHEMBL455323
SMILES | O=C(O)CCNC(=O)c1ccc(CN(c2ccc3c(c2)Cc2ccccc2-3)c2nc(-c3ccc(OC(F)(F)F)cc3)cs2)cc1 |
InChIKey | SVLDQMHFIWDPJO-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 2 |
Rotatable bonds | 10 |
Molecular weight (Da) | 629.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
glucagon | GLR | Mouse | Glucagon | B1 | pIC50 | 6.66 | 6.66 | 6.66 | ChEMBL |
glucagon | GLR | Rat | Glucagon | B1 | pIC50 | 5.75 | 5.75 | 5.75 | ChEMBL |
GIP | GIPR | Human | Glucagon | B1 | pIC50 | 6.31 | 6.42 | 6.54 | ChEMBL |
glucagon | GLR | Human | Glucagon | B1 | pIC50 | 7.23 | 7.27 | 7.3 | ChEMBL |