Chembl4578617

Chemical Properties

SMILES CC[C@H](C)[C@H](N)C(=O)N[C@H]1CCC(=O)NCCC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)[C@@H](C)CC)CCC(=O)NCCC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)NC(=O)[C@@H]2CCCN2C1=O
Hydrogen bond acceptors 30
Hydrogen bond donors 36
Rotatable bonds 58
Molecular weight 2407.4

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey CJFVEKKWSHDQON-ZWGSTEJASA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pEC50 8.37 8.37 8.37 ChEMBL
Y4 NPY4R Human Neuropeptide Y A pKi 7.2 7.2 7.2 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 7.89 7.89 7.89 ChEMBL