Chembl4592753


SMILES O=C(CN1CCN(c2ccccn2)CC1)Nc1cccnc1
InChIKey MVUXSAGLLJPWRN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 297.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.19 5.19 5.19 ChEMBL
D4 DRD4 Human Dopamine A pEC50 5.58 5.78 5.97 ChEMBL
D4 DRD4 Human Dopamine A pIC50 4.06 4.32 4.59 ChEMBL
D3 DRD3 Human Dopamine A pEC50 5.55 5.55 5.55 ChEMBL
D2 DRD2 Human Dopamine A pEC50 4.31 5.01 5.71 ChEMBL