CHEMBL437132


SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC[C@H](Cc1ccc(O)cc1)NC(C)=O)Cc1ccc(F)cc1
InChIKey HPFQGCSUEXCNCU-KUHXYZIISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 7
Rotatable bonds 19
Molecular weight (Da) 739.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 4.65 4.65 4.65 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.21 5.21 5.21 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 8.0 8.0 8.0 ChEMBL