Chembl4595855
Chemical Properties
| SMILES | N=C(N)N(CCCCN1CCN(CCCCN(Cc2ccc(C(F)(F)F)cc2)C(=N)N)CC1)Cc1ccc(C(F)(F)F)cc1 |
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 4 |
| Rotatable bonds | 14 |
| Molecular weight | 628.3 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | MYGPOFAZCBOYCJ-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H3 | HRH3 | Guinea pig | Histamine | A | pKd | 7.99 | 7.99 | 7.99 | ChEMBL |
| H1 | HRH1 | Guinea pig | Histamine | A | pKd | 7.22 | 7.22 | 7.22 | ChEMBL |