CHEMBL437490


SMILES Fc1ccc(N2CCN(Cc3cnn(-c4ccccc4)c3)CC2)cc1
InChIKey ZQEBKQUIKOLFRO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.72 5.72 5.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.54 8.54 8.54 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.27 6.27 6.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.35 6.37 6.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database