Chembl4597054

Chemical Properties

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCN(C(=O)C2CC2)c2ccc(Cc3cnc4ccccc4c3)cc21
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight 548.3

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey GFPQQDMGXUMYOM-IGYGKHONSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Rat Opioid A pKi 10.1 10.1 10.1 ChEMBL
δ OPRD Rat Opioid A pEC50 9.15 9.15 9.15 ChEMBL
μ OPRM Rat Opioid A pKi 10.3 10.3 10.3 ChEMBL
μ OPRM Rat Opioid A pEC50 9.47 9.47 9.47 ChEMBL
κ OPRK Human Opioid A pKi 7.08 7.08 7.08 ChEMBL