CHEMBL4597637


SMILES COc1ccc(F)cc1C1CC1CN(C)CCCSc1nnc(-c2ccccc2)n1C
InChIKey UQKLFSKKULYASF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.07 7.07 7.07 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.07 7.07 7.07 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.49 6.49 6.49 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database