CHEMBL4436479


SMILES Cc1cccc(NC(=O)CN2CCC(c3ccc(Cl)cc3)CC2)c1
InChIKey MGAAMGRSXKBQAO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 342.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.94 6.94 6.94 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.58 4.58 4.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 4.15 4.26 4.37 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.15 4.15 4.15 ChEMBL