Chembl4638599

Chemical Properties

SMILES O=c1n(CCCCN2CCN(c3cccc4sccc34)CC2)nc2ccccn12
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight 407.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey SPMHWCSUNSWHDK-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pIC50 7.82 7.82 7.82 ChEMBL
H1 HRH1 Human Histamine A pIC50 7.05 7.05 7.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 8.77 8.77 8.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.47 7.47 7.47 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.91 7.91 7.91 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.87 7.87 7.87 ChEMBL