CHEMBL4635603


SMILES c1ccc2oc(SCCCCCCN3CCN(c4nsc5ccccc45)CC3)nc2c1
InChIKey JGJOJEUMPBPYKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.52 6.52 6.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database