LACIDIPINE


SMILES CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1/C=C/C(=O)OC(C)(C)C
InChIKey GKQPCPXONLDCMU-CCEZHUSRSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 455.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 5.68 5.68 5.68 ChEMBL
A3 AA3R Human Adenosine A pKi 5.64 5.64 5.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.25 8.25 8.25 Drug Central
A3 AA3R Human Adenosine A pKi 8.25 8.25 8.25 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 5.21 5.21 5.21 ChEMBL
A3 AA3R Human Adenosine A pIC50 5.39 5.39 5.39 ChEMBL