CHEMBL4650683


SMILES C[N+]12CCC(CC1)[C@@H](OC(=O)Nc1ccc(F)cc1-c1ccc(F)c(Cl)c1)C2
InChIKey KBNPGVPUYYZVTB-VUKQLWBESA-O

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 407.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.15 10.15 10.15 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.43 8.43 8.43 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.92 9.92 9.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pEC50 8.17 8.41 8.66 ChEMBL