CHEMBL464192


SMILES O=C1N(CCN2CCCCC2)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey AWCUCKNTBFFHCS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 576.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.1 8.1 8.1 ChEMBL
δ OPRD Human Opioid A pKi 5.5 5.5 5.5 ChEMBL
κ OPRK Human Opioid A pKi 6.55 6.55 6.55 ChEMBL
μ OPRM Human Opioid A pKi 6.17 6.17 6.17 ChEMBL
NOP OPRX Human Opioid A pKi 8.1 8.1 8.1 PDSP Ki database
κ OPRK Human Opioid A pKi 6.55 6.55 6.55 PDSP Ki database
μ OPRM Human Opioid A pKi 6.17 6.17 6.17 PDSP Ki database
δ OPRD Human Opioid A pKi 5.5 5.5 5.5 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database